While there's no doubt the injuries have hurt us, I don't think we necessarily have to lower our expectations.
As I see it Emi B was likely a rotation option once Ramsey was back. So as long as we get a creative midfielder in we should be no weaker there.
Now obviously the Mings injury is a different story. The leader and rock of our defence and we're going to be without him for the season. However his replacement is one of the best defenders in Europe. So as long as someone takes up a leadership role back there (maybe Carlos?) again there's no reason why we should be any weaker there either.
No reason why we can't have a really good season, I'm still backing us to win a trophy and challenge for Europe